The purpose of this research is to determine indicators for innovation survey in the field of biotechnology in Iran. In order to achieve this goal, theoretical basics on innovation survey are required to be studied to reach the needed indicators. Finally, with a view to the advantages and weaknesses of the innovation survey procedures and also on the basis of a comparative study in the approaches so far presented, the OECD's indicators are examined through some adjustments for innovation survey in the field of biotechnokogy in Iran. The research method used is descriptive-analytical and can be placed in the applied research. The statistical population consists of research-academic centers and active biotechnology companies. Research data is collected by questionnaire with 87% of reliability coefficient. The data was analyzed by the Fuzzy Hypothesis Test procedure. According to the research results, the indicator needed for innovation survey in the field of biotechnology in Iran can be divided into eight fields of R&D and investment in knowledge, human resources, innovation policy, innovation performance, information and communication technology, globalization, global economic flows, productivity and trade. The possibility of effectiveness of each of the indicators is determined according to their membership degree of acceptance in the Fuzzy environment.